Cecilia Puga graduated in architecture at the Pontificia Universidad Católica de Chile in 1990. Between 1987 and 1989 she took courses in history and restoration of architectural monuments at the Universitá della Sapienza in Rome.
She has won awards as an architect in competitions like the Centro Cultural Estación Mapocho (1992, 3rd prize) along with D. Prieto, S. Álvarez and D. Rodríguez; in the new Auditorium and Library of the Faculty of Architecture, Design and Urban Studies of the Pontificia Universidad Católica de Chile (1995, 1st prize), together with T. Fernández and S. Radic; and in the Council building for the Municipality of Vitacura (2000, 1st honorable mention) together with S. Radic, G. Puga and R. Serpell.
Her professional works have been exhibited in Chile and the USA, and they include single-family houses, an apartment building, store and office interiors, a chapel and a master plan to recover old Cono Sur winery buildings in Chimbarongo, where she also built an entrance pavilion, a dining area and a barrel room. Between 2003 and 2006 she developed the project for the second stage of the Sergio Larrain García Moreno information center at the Faculty of Architecture, Design and Urban Studies of the PUC.
She has lectured at the Pontificia Universidad Católica de Chile and Universidad Nacional Andrés Bello in Santiago, and in 2007 was a guest lecturer at the University of Texas School of Architecture in Austin, USA.
From 1990 to 1993 she was the editor of the magazine CA published by the Colegio de Arquitectos de Chile, and she was also Director of the School of Architecture at Universidad Nacional Andrés Bello.